Publications and Funding
Publications (* denotes undergraduate researchers)
• Eric M.B. Brown, Tatjana Paunesku, AiGuo Wu, K. Ted Thurn, Tierra Hatcher*, Caroline Doty, Hans Arora, Ye Yuan, and Gayle Woloschak. Tunable Photodynamic Cleavage of Target DNA Using Modified Alizarin Red S-Peptide Nucleic Acid-TiO2 Nanoconjugates. In preparation.
• Eric M.B. Brown, Latoya L. Allen*, Harley Pyles*, Jessica Solis*, Traci A. Wileman*, and Gail B. Willadsen*. Advancements in using TiO2 bionanoconjugates for precision degradation of intracellular biological structures. Submitted 2012.
• Jay Blatnik*, Lanette Luebke*, Stephanie Simonet*, Megan Nelson*, Race Price*, Rachael Leek*, Leyong Zeng, Aiguo Wu, Eric M. B. Brown. Dye Surface Coating Enables Visible Light Activation of TiO2 Nanoparticles Leading to Degradation of Neighboring Biological Structures. Microscopy and Microanalysis. v18, 134-142, 2012. *Selected as ‘First View’ Article* PDF
• Kenneth T. Thurn, Hans Arora, Tatjana Paunesku, Aiguo Wu, Eric M. B. Brown, Caroline Doty, Jeff Kremer, Gayle Woloschak. Endocytosis of Titanium Dioxide Nanoparticles in Prostate Cancer PC-3M Cells. Nanomedicine: Nanotechnology, Biology, and Medicine. Vol. 7, Issue 2, April 2011. *Feature Article & Cover Picture* PDF
• Caroline Doty, Eric Brown, Aiguo Wu, Tatjana Paunesku, Gayle Woloschak. Effects of Fluorescent Dye Coating of Metal Oxide Nanoparticles on DNA Scission. The Journal of the Robert H. Lurie Comprehensive Cancer Center. Vol. 13. 2009.
• Eric M. B. Brown. Evaluation of the Sequence-Specific DNA Hybridization and Cleavage Capabilities of Peptide Nucleic Acid-Titanium Dioxide (PNA-TiO2) Nanoconjugates. ProQuest/UMI Publishing Company. 2009. Available Upon Request
• Kenneth T. Thurn, Tatjana Paunesku, Aiguo Wu, Eric M.B. Brown, Barry Lai, Stefan Vogt, Jörg Maser, Mohammed Aslam, Vinayak Dravid, Raymond Bergan, Gayle Woloschak. Labeling TiO2 nanoparticles with dyes for optical fluorescence microscopy and determination of TiO2-DNA nanoconjugate stability. Small. v5, No. 11, 1318-1325, 2009. PDF
• Eric M.B. Brown, Tatjana Paunesku, AiGuo Wu, K. Ted Thurn, Benjamin Haley, Jimmy Clark*, Taisa Priester*, and Gayle Woloschak. Methods for assessing DNA hybridization of PNA-TiO2 nanoconjugates. Analytical Biochemistry. v383, 226-235, 2008. PDF
• Aiguo Wu, Tatjana Paunesku, Eric M. B. Brown, Angela Babbo, Cecille Cruz*, Mohamed Aslam, Vinayak Dravid, and Gayle E. Woloschak. Titanium dioxide nanoparticles assembled by DNA molecules hybridization and loading of DNA interacting proteins. Nano. Vol 3, No. 1. 2008. PDF
• K. Ted Thurn, Eric M.B. Brown, Aiguo Wu, Stefan Vogt, Barry Lai, Jörg Maser, Tatjana Paunesku, Gayle E. Woloschak. Nanoparticles for Applications in Cellular Imaging. Nanoscale Research Letters. 2007. PDF
• Eric M. B. Brown. The effects of elevated atmospheric CO2-altered, microbially colonized leaf litter on shredder macroinvertebrates fecal quality in streams: implications on downstream collector macroinvertebrates. Heckman Bindery, Inc. 2006. Available Upon Request
Funding
• UW-Whitewater High-Cost Undergraduate Research Grant - Assessing Cellular Responses of HeLa (cervical cancer) Cells To Activated Fe3O4-TiO2 Core-Shell Nanoparticles. (Awarded to Kara Kamps and Eric Brown PI; October 1, 2011 – May 10, 2012.)
• Wisys Applied Research Grant-WiTAG Match Grant - Applying Dye-Coated and Core-Shell Dye-Coated Titanium Dioxide Nanoparticles to Enhance Cleaning and Bio-decontamination of Surfaces via Visible Light Activated Self-sterilization. (Awarded to Eric Brown PI; July 1, 2011 – June 30, 2012)
• Innovation Hub Fellowship – Nanotechnology/Business Partnership Developemnt Through Atomic Force Microscopy. (Awarded to Eric Brown PI; Summer 2011; respectfully declined)
• Prototype Development Grant - Development of an 'application coating' to apply fluorescently labeled titanium dioxide (Ti02) nanoparticles to surfaces for self-sterilization. (Awarded to Eric Brown PI; May 12, 2011 – August 31, 2011)
• Grant Writing Fellowship – Summer 2011 (Award to Eric Brown PI; May 23, 2011 – July 31, 2011)
• Undergraduate Research Mentors Program – (Awarded to Eric Brown PI; April - May 2011)
• Just in Time Travel Grant – NSF Meeting (Awarded to Eric Brown PI, December 28, 2010 – February 1, 2011)
• Library Research Fellowship - Development of fluorescently labeled titanium dioxide (Ti02) nanoparticles to enhance cleaning and bio-decontamination of surfaces. (Awarded to Eric Brown PI, September 8, 2010 – September 8, 2011)
• Just in Time Travel Grant – Present and Participate at the Wisconsin Science and Technology Symposium (Awarded to Eric Brown PI, June 8, 2010 – August 15th, 2010)
• Applied Research Grant - Development of fluorescently labeled titanium dioxide (Ti02) nanoparticles to enhance cleaning and bio-decontamination of surfaces (Awarded to Eric Brown PI, July 1, 2010 – June 30, 2011)
• Grant Writing Fellowship – Summer 2010 Wisys Grant Writing Workshop (Award to Eric Brown PI, May 1, 2010 – June 30, 2011)
• Microscopy Society of America Scholarship Award – Dye-nanoparticle conjugates for use in live cell imaging of cancer cells and alternative microscopy excitation light sources (Award to Jay Blatnik and Eric Brown PI, April 1, 2010-December 31, 2010)
• Just in Time Grant - UWW Nanoscience Symposium (Awarded to Eric Brown coPI, Jalal Nawash, and Magaret Phillips, March 24, 2010 – December 30, 2010)